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publication
Exprese genu pro asparagin synthetasu a vztah k citlivosti na L-asparaginasu u buněk akutních lymfoblastických leukemií
Publikace bez příslušnosti k fakultě
publication
Optimizing asparaginase therapy for acute lymphoblastic leukemia
2013 |
2. lékařská fakulta
publication
Pancreatitis-associated protein as an early marker of asparaginase-associated pancreatitis
2021 |
2. lékařská fakulta, Fakulta tělesné výchovy a sportu, 1. lékařská fakulta
publication
Metabolic profile of leukemia cells influences treatment efficacy of L-asparaginase
2020 |
2. lékařská fakulta
publication
Pre-existing antibodies against polyethylene glycol reduce asparaginase activities on first administration of pegylated E. coli asparaginase in children with acute lymphocytic leukemia
2022 |
Publikace bez příslušnosti k fakultě
publication
Odlišné hladiny asparagin syntetázy nejsou zodpovědné za rozdílnou senzitivitu leukemických blastů k L-Asparagináze
2010 |
2. lékařská fakulta
publication
Upregulation of asparagine synthetase fails to avert cell cycle arrest induced by L-asparaginase in TEL/AML1-positive leukaemic cells
2004 |
2. lékařská fakulta
publication
PTEN/PI3K/Akt pathway alters sensitivity of T-cell acute lymphoblastic leukemia to L-asparaginase
2022 |
2. lékařská fakulta
publication
Asparagine levels in the cerebrospinal fluid of children with acute lymphoblastic leukemia treated with pegylated-asparaginase in the induction phase of the AIEOP-BFM ALL 2009 study
2019 |
2. lékařská fakulta
publication
Restored biosynthetic pathways induced by MSCs serve as rescue mechanism in leukemia cells after L-asparaginase therapy
2023 |
2. lékařská fakulta, Přírodovědecká fakulta
publication
Therapeutic Drug Monitoring of Asparaginase: Intra-individual Variability and Predictivity in Children With Acute Lymphoblastic Leukemia Treated With PEG-Asparaginase in the AIEOP-BFM Acute Lymphoblastic Leukemia 2009 Study
2020 |
2. lékařská fakulta
publication
Population Pharmacokinetics of PEGylated Asparaginase in Children with Acute Lymphoblastic Leukemia: Treatment Phase Dependency and Predictivity in Case of Missing Data
2021 |
2. lékařská fakulta
publication
Therapeutic Drug Monitoring of Asparaginase Activity-Method Comparison of MAAT and AHA Test Used in the International AIEOP-BFM ALL 2009 Trial
2018 |
Publikace bez příslušnosti k fakultě
publication
Impact of Antibodies Against Polyethylene Glycol on the Pharmacokinetics of PEGylated Asparaginase in Children with Acute Lymphoblastic Leukaemia: A Population Pharmacokinetic Approach
2022 |
Publikace bez příslušnosti k fakultě
publication
Testing of L-asparaginase cytostatic effect on TEL/AML1-positive and -negative cells
Publikace bez příslušnosti k fakultě
publication
Four Additional Doses of PEG-L-Asparaginase During the Consolidation Phase in the AIEOP-BFM ALL 2009 Protocol Do Not Improve Outcome and Increase Toxicity in High-Risk ALL: Results of a Randomized Study
2024 |
2. lékařská fakulta
publication
Incidence and Characteristics of Hypersensitivity Reactions to PEG-asparaginase Observed in 6136 Children With Acute Lymphoblastic Leukemia Enrolled in the AIEOP-BFM ALL 2009 Study Protocol
2023 |
2. lékařská fakulta
publication
Antiproferative in vitro effect of L-asparaginase on leukemic cells with t(12;21)
Publikace bez příslušnosti k fakultě
publication
Effect of L-asparaginase in TEL/AML1-(plus) subpopulation of childhood ALL
Publikace bez příslušnosti k fakultě
publication
Asparagine Synthetase Gene and Tel/AML1 Gene: Expression kinetics after L-Asparaginase Administration in TEL/AML1-Positive cells
Publikace bez příslušnosti k fakultě
publication
Asparagine Synthetase Gene and Tel/AML1 Gene: Expression kinetics after L-Asparaginase Administration in TEL/AML1-Positive cells
2001 |
Fakulta tělesné výchovy a sportu
publication
Can Machine Learning Models Predict Asparaginase-associated Pancreatitis in Childhood Acute Lymphoblastic Leukemia
2022 |
2. lékařská fakulta
publication
Asparaginase-associated pancreatitis in childhood acute lymphoblastic leukaemia: an observational Ponte di Legno Toxicity Working Group study
2017 |
Publikace bez příslušnosti k fakultě
publication
Pharmacological inhibition of fatty-acid oxidation synergistically enhances the effect of L-asparaginase in childhood ALL cells
2016 |
2. lékařská fakulta, Přírodovědecká fakulta, Ústřední knihovna
publication
Influence of cancer metabolism on the therapy of childhood leukaemia
2018 |
2. lékařská fakulta
publication
TEL/AML1 increases sensitivity of leukemia cells to L-Asparginase by induction of metabolic stress
2006 |
2. lékařská fakulta, Fakulta tělesné výchovy a sportu, 1. lékařská fakulta
publication
Low expression of asparagine synthetase in lymphoid blasts precludes its role in sensitivity to L-asparaginase
2012 |
2. lékařská fakulta
publication
Sledování toxicity L-asparaginázy u dospělých pacientů s akutní lymfoblastickou leukémií
Publikace bez příslušnosti k fakultě
publication
Trypsin-encoding PRSS1-PRSS2 variations influence the risk of asparaginase-associated pancreatitis in children with acute lymphoblastic leukemia: a Ponte di Legno toxicity working group report
2019 |
Publikace bez příslušnosti k fakultě
publication
Chemical degradation of wastes of antineoplastic agents Amsacrine, Azathioprine, Asparaginase and Thiotepa
Publikace bez příslušnosti k fakultě