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Reactive metabolites
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publication
Cytochrome P450 and peroxidase oxidise detoxication products of carcinogenic aristolochic acids (aristolactams) to reactive metabolites binding to DNA in vitro
1995 |
First Faculty of Medicine, Faculty of Mathematics and Physics
publication
Hepatotoxicity of monoterpenes and sesquiterpenes
2018 |
Faculty of Pharmacy in Hradec Králové
publication
Serum Level of Antibodies (IgG, IgM) Against Benzo[a]pyrene-7,8-diol-9,10-epoxide-DNA Adducts in Children Dermatologically Exposed to Coal Tar
2017 |
First Faculty of Medicine, Faculty of Medicine in Hradec Králové
publication
Study of posttranslational non-enzymatic modifications of collagen using capillary electrophoresis/mass spectrometry and high performance liquid chromatography/mass spectrometry
2007 |
First Faculty of Medicine, Faculty of Physical Education and Sport
publication
Cytochrome P450 destruction by benzene metabolites 1,4-benzoquinone and 1,4-hydroquinone and the formation of hydroxyl radicals in minipig liver microsomes
2007 |
First Faculty of Medicine, Central Library of Charles University, Third Faculty of Medicine
publication
Induced expression of microsomal cytochrome b(5) determined at mRNA and protein levels in rats exposed to ellipticine, benzo[a]pyrene, and 1-phenylazo-2-naphthol (Sudan I)
2016 |
Faculty of Science
publication
Ellipticine-loaded apoferritin nanocarrier retains DNA adduct-based cytochrome P450-facilitated toxicity in neuroblastoma cells
2019 |
Faculty of Science, Second Faculty of Medicine
publication
Cytochrome P450-and peroxidase-mediated oxidation of anticancer alkaloid ellipticine dictates its anti-tumor efficiency
2011 |
Faculty of Science
publication
Metabolic Gene Variants Associated with Chromosomal Aberrations in Healthy Humans
2015 |
First Faculty of Medicine, Second Faculty of Medicine
publication
Application of hepatic cytochrome b(5)/P450 reductase null (HBRN) mice to study the role of cytochrome b(5) in the cytochrome P450-mediated bioactivation of the anticancer drug ellipticine
2019 |
Faculty of Science