Lecturers

Lectures

Organisation of living systems – definition of life, cell theory. Models in biomedicine. Prokaryotic and eukaryotic cells.
DNA synthesis.

Expression of genetic information 1 – transcription,post-transcriptional modifications of RNA
Expression of genetic information 2 – transcription, post-transcriptional modifications of RNA, translation, post-translational modifications of proteins.
Cell membranes – structure and function of biological membranes, membrane transport, membraneous organelles of eukaryotic cells.
Mitochondrion – structure and function, ATP production.
Cytoskeleton – microtubules, microfilaments, intermediate filaments, cellular movements, transport of vesicles.
Regulation of cellular functions – principles, signals, receptors, signaling pathways, regulation of gene expression.
Cell cycle - course and regulation.
Cell death.
Introduction to genetics – genes, genomes, variability of individuals. Mutations, polymorphisms, reparatory mechanisms.
Human genome – organisation of genome, chromosomes, structure of chromatin and its changes.
Meiosis.

Practical courses & seminars

Lecturers

Practical course

1. Microscopic techniques I.

1.1 General terms and conditions of the biology course

1.2 Size estimation

1.3 Permanent mount of cells cultivated in vitro

2. Microscopic techniques II.

2.1 Wet mount of buccal cells

3. Cellular membranes – osmotic phenomena

3.1 Osmotic changes in erythrocytes after the treatment with anisotropic solutions

3.2 Plasmolysis in plant cell (Elodea densa)

4. Cell motility

4.2 Cyclosis in plant cells (Elodea densa)

4.3 Amoeboid movement

4.4 Flagellar movement

5. Cell cultures in biomedicine (seminar)

5.1 Cell and tissue culture techniques

6. Information sources and their relevance in biomedicine (seminar)

6.1 Scientific information in biomedicine – the structure of scientific article

6.2 In vitro tests used for cytotoxicity assays – dental applications

7. Cell death – scientific methodology

7.1 Permanent mount of tumor cells treated with cytostatic drug

7.2. Vital staining

8. Cell cycle and cell division

8.1 Mitosis in permanent mounts of plant cells

8.2 Mitosis in animal cell cultures

8.3 Mitotic index and particular phases of mitosis

9. Advances in biosciences (seminar)

9.1 Student presentations (biodentistry oriented)

10. CREDIT

10.1 Final test