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CYP3A4
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publication
Azole antimycotics differentially affect rifampicin-induced pregnane X receptor-mediated CYP3A4 gene expression
2008 |
Central Library of Charles University
publication
Valproic acid induces CYP3A4 and MDR1 gene expression by activation of constitutive androstane receptor and pregnane X receptor pathways
2007 |
Publication without faculty affiliation
publication
Examination of glucocorticoid receptor alpha-mediated transcriptional regulation of P-glycoprotein, CYP3A4, and CYP2C9 genes in placental trophoblast cell lines
2007 |
Publication without faculty affiliation
publication
Rifampicin-Activated Human Pregnane X Receptor and CYP3A4 Induction Enhance Acetaminophen-Induced Toxicity
2009 |
First Faculty of Medicine
publication
Measurement of cytochrome CYP3A4 activity in patients with venticular tachyarrythmias
Publication without faculty affiliation
publication
Bioinformatic analysis of miRNAs targeting the key nuclear receptors regulating CYP3A4 gene expression: The challenge of the CYP3A4 "missing heritability" enigma
2015 |
Faculty of Pharmacy in Hradec Králové
publication
Intestinal cell-specific vitamin D receptor (VDR)-mediated transcriptional regulation of CYP3A4 gene
2010 |
Central Library of Charles University
publication
Modelování změn farmakokinetických vlastností substrátů CYP3A4 při jejich kombinaci se silnými inhibitory
2015 |
First Faculty of Medicine
publication
Vliv polymorfizmu CYP3A4 na farmakologické vlastnosti amiodaronu
Publication without faculty affiliation
publication
Pharmacogenetics of nuclear receptor in CYP3A4 gene regulation
Publication without faculty affiliation
publication
Metformin suppresses pregnane X receptor (PXR)-regulated transactivation of CYP3A4 gene
2011 |
Faculty of Pharmacy in Hradec Králové
publication
Drug interactions of grapefruit juice and selected phytopharmacs
2007 |
Third Faculty of Medicine
publication
Roles of CYP3A4, CYP3A5 and CYP2C8 drug-metabolizing enzymes in cellular cytostatic resistance
2021 |
Faculty of Pharmacy in Hradec Králové
publication
alfa-naftoflavon jako modelový ligand aktivního centra cytochromu P450 CYP3A4 a CYP3A6
2001 |
Faculty of Science
publication
alfa-naftoflavon jako modelový ligand aktivního centra cytochromu P450 CYP3A4 a CYP3A6
2001 |
First Faculty of Medicine, Faculty of Mathematics and Physics
publication
Azole antimycotics differentially affect rifampicin-induced pregnane X receptor-mediated CYP3A4 gene expression
2008 |
Faculty of Pharmacy in Hradec Králové, Central Library of Charles University
publication
Perorální antikoagulancia, jejich lékové interakce a dávkování u pacientů s fibrilací síní
2015 |
Third Faculty of Medicine
publication
Catalytic activity of human CYP1A1 and CYP3A4 expressed in baculovirus system
2003 |
Faculty of Pharmacy in Hradec Králové
publication
Valproic acid induces CYP3A4 expression through Pregnane X (PXR) and Constitutive androstane (CAR) nuclear receptor pathways
Publication without faculty affiliation
publication
Entrectinib reverses cytostatic resistance through the inhibition of ABCB1 efflux transporter, but not the CYP3A4 drug-metabolizing enzyme
2020 |
Faculty of Pharmacy in Hradec Králové
publication
Influence of metabolic polymorphism of cytochrome CYP3A4 on pharmacokinetic properties of amiodarone
Publication without faculty affiliation
publication
Investigation of Orlistat effects on PXR activation and CYP3A4 expression in primary human hepatocytes and human intestinal LS174T cells
2010 |
Central Library of Charles University
publication
Valproic acid induces CYP3A4 and MDR1 gene expression by activation of constitutive androstane receptor and pregnane X receptor pathways
2007 |
Faculty of Pharmacy in Hradec Králové
publication
Examination of glucocorticoid receptor alpha-mediated transcriptional regulation of P-glycoprotein, CYP3A4, and CYP2C9 genes in placental trophoblast cell lines
2007 |
Faculty of Pharmacy in Hradec Králové, Central Library of Charles University
publication
Role of extracellular-signal regulated kinase (ERK) pathway in PXR-mediated valproic acid-induced activation of CYP3A4 expression
Publication without faculty affiliation
publication
Identification of Enzymes Oxidizing the Tyrosine Kinase Inhibitor Cabozantinib: Cabozantinib Is Predominantly Oxidized by CYP3A4 and Its Oxidation Is Stimulated by cyt b(5) Activity
2020 |
Faculty of Science
publication
Gene Expression Profiling of 1alpha,25(OH)2D3 Treatment in 2D/3D Human Hepatocyte Models Reveals CYP3A4 Induction but Minor Changes in Other Xenobiotic-Metabolizing Genes
2022 |
Faculty of Pharmacy in Hradec Králové, Faculty of Medicine in Pilsen
publication
Non-target biotransformation enzymes as a target for triazole-zinc mixtures
2023 |
Faculty of Science
publication
CYP2C19 and CYP3A4 activity and ADP-induced platelet reactivity in prasugrel- or ticagrelor-treated STEMI patients: monocentric study in PRAGUE-18 trial participants
2020 |
Third Faculty of Medicine
publication
Benzodiazepines medazepam and midazolam are activators of pregnane X receptor and weak inducers of CYP3A4: Investigation in primary cultures of human hepatocytes and hepatocarcinoma cell lines
2010 |
Central Library of Charles University