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oximes
Publication
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Person
Publication
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publication
A comparison of reactivation and therapeutic efficacy of the oxime K203 and its fluorinated analog (KR-22836) with currently available oximes (obidoxime, trimedoxime, HI-6) against tabun in rats and mice
2010 |
Faculty of Medicine in Hradec Králové
publication
Effect of oximes used by therapy of poisoning of organophosphates at agregation of human trombocytes in vitro
Publication without faculty affiliation
publication
Capability testing of well-known oximes (pralidoxime, trimedoxime, HI-6, methoxime, obidoxime) to reactivate in vitro chlorpyrifos-inhibited acetylcholinesterase
Publication without faculty affiliation
publication
Potency of several oximes to reactivate human acetylcholinesterase and butyrylcholinesterase inhibited by paraoxon in vitro
2008 |
Central Library of Charles University
publication
Potency of novel oximes to reactivate sarin inhibited human cholinesterases
2008 |
Central Library of Charles University
publication
The influence of combinations of oximes on the reactivating and therapeutic efficacy of antidotal treatment of soman poisoning in rats and mice
2009 |
Faculty of Medicine in Hradec Králové
publication
Bisquaternary oximes as reactivators of tabun-inhibited human brain cholinesterases: an in vitro study
2007 |
Publication without faculty affiliation
publication
The influence of combinations of oximes on the reactivating and therapeutic efficacy of antidotal treatment of tabun poisoning in rats and mice
2010 |
Faculty of Medicine in Hradec Králové
publication
Vasorelaxant activity of some oxime derivatives
2007 |
Faculty of Science
publication
Therapeutic and reactivating efficacy of oximes K027 and K203 against a direct acetylcholinesterase inhibitor
2016 |
Publication without faculty affiliation
publication
Effect of P-glycoprotein on the availability of oxime reactivators in the brain
2020 |
Publication without faculty affiliation
publication
A Comparison of the Neuroprotective and Reactivating Efficacy of a Novel Bispyridinium Oxime K870 with Commonly Used Pralidoxime and the Oxime HI-6 in Tabun-Poisoned Rats
2021 |
Publication without faculty affiliation
publication
Could oxime HI-6 really be considered as 'broad-spectrum' antidote?
2009 |
Central Library of Charles University
publication
Toxicity, pharmacokinetics, and effectiveness of the ortho-chlorinated bispyridinium oxime, K870
2022 |
Publication without faculty affiliation
publication
Current approaches to enhancing oxime reactivator delivery into the brain
2019 |
Publication without faculty affiliation
publication
The Evaluation of the Reactivating and Neuroprotective Efficacy of Two Newly Prepared Bispyridinium Oximes (K305, K307) in Tabun-Poisoned Rats-A Comparison with Trimedoxime and the Oxime K203
2017 |
Publication without faculty affiliation
publication
Oximes: Inhibitors of Human Recombinant Acetylcholinesterase. A Structure-Activity Relationship (SAR) Study
+1
2013 |
Publication without faculty affiliation
publication
Novel acetylcholinesterase reactivator - oxime K048 - reactivation activity in vitro
2010 |
Central Library of Charles University
publication
Strategies for enhanced bioavailability of oxime reactivators in the central nervous system
2023 |
Publication without faculty affiliation
publication
Halogen substituents enhance oxime nucleophilicity for reactivation of cholinesterases inhibited by nerve agents
2022 |
Publication without faculty affiliation
publication
Universality of Oxime K203 for Reactivation of Nerve Agent-Inhibited AChE
2015 |
Publication without faculty affiliation
publication
Reactivation kinetics of 31 structurally different bispyridinium oximes with organophosphate-inhibited human butyrylcholinesterase
2015 |
Publication without faculty affiliation
publication
Chemoenzymatic one-pot reaction from carboxylic acid to nitrile via oxime
2021 |
Central Library of Charles University, Faculty of Science
publication
The interaction of standard oxime reactivators with hemicholinium-3 sensitive choline carriers
2012 |
Publication without faculty affiliation
publication
Reactivation of human brain homogenate cholinesterases inhibited by tabun using newly developed oximes K117 and K127
+1
2009 |
Central Library of Charles University
publication
Investigation of the reactivation kinetics of a large series of bispyridinium oximes with organophosphate-inhibited human acetylcholinesterase
2016 |
Publication without faculty affiliation
publication
Oxime K203: a drug candidate for the treatment of tabun intoxication
2019 |
Publication without faculty affiliation
publication
Partition of bispyridinium oximes (trimedoxime and K074) administered in therapeutic doses into different parts of the rat brain
2011 |
Publication without faculty affiliation